CAS No. 933041-13-5|4-Bromo-6-chloropyridazin-3(2H)-ib

Taw qhiathiab daim ntawv thovntawm CAS No. 933041-13-5|4-Bromo-6-chloropyridazin-3(2H)-ib

4-Bromo-6-chloropyridazin-3(2H)-ib qho yog glycosylation inhibitor thiab nucleoside analogue uas tuaj yeem siv los kho mob qog noj ntshav. Nws inhibits cov synthesis ntawm deoxyribonucleotides los ntawm ribonucleotides los ntawm kev khi rau lub enzyme ribonucleotide reductase, uas catalyzes hloov dua siab tshiab ntawm ribonucleotides rau deoxynucleotides.

4-Bromo-6-chloropyridazin-3(2H)-ib qho tau pom tias inhibit glycosylation hauv nas lub siab hlwb. Cov tshuaj no tseem inhibits acetone thiab glycosidation, uas yog cov tshuaj tiv thaiv uas tsim cov piam thaj los ntawm cov amino acids lossis carbohydrates. Cov txheej txheem crystallization kuj inhibited los ntawm cov tshuaj no vim nws tiv thaiv kev tsim ntawm nucleoside crystals, uas koom nrog DNA replication thiab cell division.

Synonyms:

5-bromo-3-chloro-1H-pyridazin-6-ib qho;

Specification ntawm CAS No. 933041-13-5|4-Bromo-6-chloropyridazin-3(2H)-ib

Package ua thiab kev thauj mus losntawm Kev Taw Qhia thiab kev siv ntawmCAS No. 933041-13-5|4-Bromo-6-chloropyridazin-3(2H)-ib

Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg

Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv

Cov ntawv txheebntawmCAS No. 933041-13-5|4-Bromo-6-chloropyridazin-3(2H)-ib

Tsim thiab Tshawb Nrhiav N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl){{7} }(trifluoromethyl) isonicotinamide, ib qho Selective, Efficacious, thiab Zoo ...

S Ramurthy, BR Taft, RJ Aversa, PA Barsanti… - 2019 - ACS Publications

... mus rau 80% EtOAc: heptanes kom tawm los 4-bromo-6-chloropyridazin-3(2H)-one (1.42 g, 6.78 mmol) ...

Rau ib qho kev daws ntawm 4-bromo-6-chloropyridazin-3(2H)-ib (500 mg, 2.387 mmol) thiab Cs 2 CO 3 ...

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