Taw qhiathiab daim ntawv thovntawm CAS No. 873054-44-5|Ivacaftor
Qhib CFTR channels.
Ivacaftor (lub npe lag luam Kalydeco, tsim los ua VX-770) yog ib qho tshuaj siv los kho cystic fibrosis hauv cov neeg uas muaj qee yam kev hloov pauv hauv cystic fibrosis transmembrane conductance regulator (CFTR) noob, uas suav txog 4-5% ntawm cov mob cystic. fibrosis, thiab muaj nyob rau hauv cov tshuaj ua ke, lumacaftor / ivacaftor, uas yog siv los kho cov neeg mob cystic fibrosis uas muaj F508del kev hloov hauv CFTR.
Synonyms:
VX770,VX 770,Ivacaftor;Ivacaftor;[14C]-Ivacaftor;
N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide;
Kalydeco;VX770;Ivacaftor (VX-770);UNII-1Y740ILL1Z;
N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline{{9} }carboxaraide;
N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline{{9} carboxamide;
N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide;
N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide;
Specification ntawm CAS No. 873054-44-5|Ivacaftor
|
Yam khoom |
SPECIFICATION |
|
CAS |
873054-44-5 |
|
MF |
C24H28N2O3 |
|
MW |
392.49 |
|
Melting point |
212-215 degree |
|
Boiling point |
55 0.4 ± 50.0 degree (Predicted) |
|
Qhov ntom |
1.187 |
|
acidity coefficient (pKa) |
11. |
Package ua thiab kev thauj mus losntawm Kev Taw Qhia thiab kev siv ntawmCAS No. 873054-44-5|Ivacaftor
Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
Cov ntawv txheebntawmCAS No. 873054-44-5|Ivacaftor
Ivacaftor
PB Davis, U Yasothan, P Kirkpatrick - Nature reviews Drug discovery, 2012 - go.gale.com
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