Taw qhiathiab daim ntawv thovntawm CAS 28822-58-4 |3-ISOBUTYL-1-METHYLXANTHINE
Bioactive IBMX (Isobutylmethylxanthine, 1-methyl-3- isobutylxanthine) yog ib qho uas tsis yog-pioneer phosphodiesterase (PDE) conjugate Chemicalbook, nrog IC50 qhov tseem ceeb rau PDE3, PDE4, thiab PDE5 feem. Nws yog 6.5 ± 1.2, 26.3 ± 3.9 thiab 31.7 ± 5.3μM. Nws tuaj yeem txhim kho intracellular cAMP qib thiab yog adenosine (A1) receptor antagonist.
Siv: Cyclic nucleotide phosphodiesterase protein inhibitor. Lub hom phiaj Tsis yog tshwj xeeb inhibitor ntawm cAMP thiab cGMP phosphodiesterases. IBMX inhibits phosphodiesterase, thiab qhov nce hauv cAMP activates PKA, uas ua rau txo qis kev loj hlob, nce kev sib txawv thiab induction ntawm apoptosis. IBMX inhibits tryptamine induced los ntawm phenylephrine (txo cov hnoos qeev los ntawm neuroendocrine epithelial hlwb). IC50: 1.3μM) txo. Kuj tseem ua raws li adenosine receptor antagonist.
Specification ntawm CAS 28822-58-4 |3-ISOBUTYL-1-METHYLXANTHINE
|
CAS |
28822-58-4 |
|
Qhov tshwm sim |
Dawb hmoov |
| Kub point, degree | 363.42 degree (kev kwv yees ntxhib) |
|
Melting point, degree |
200-201 degree (lit.) |
|
Qhov ntom |
1.2042 (kev kwv yees kwv yees) |
Pob thiab kev thauj mus losntawm CAS 28822-58-4 |3-ISOBUTYL-1-METHYLXANTHINE
Pob: 25kg / 100kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
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3-Isobutyl-1-methylxanthine 3-Isobutyl-1-methylxanthine A cell-permeable, non-specific inhibitor ntawm cAMP thiab cGMP phosphodiesterases (IC₅₀=2-50 µM). CAS Nr .:28822-58-4; Synonyms ...
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