CAS: 13101-83-2|6-Fluoronaphthalen-2-Ol

Taw qhia ntawm CAS: 13101-83-2|6-fluoronaphthalen-2-ol

Fluoro-substituted naphthalenes yog ib chav kawm ntawm cov tshuaj tsw qab uas muaj cov fluorine atoms rau hauv lub nplhaib naphthalene. Cov tebchaw no nthuav tawm lub cev, tshuaj, thiab hluav taws xob tshwj xeeb vim muaj cov fluorine, uas yog electronegative heev. Cov chav kawm ntawm cov tebchaw no pom cov ntawv thov hauv cov ntaub ntawv tshawb fawb, tshuaj, thiab cov khoom siv hluav taws xob organic vim lawv qhov hloov pauv hloov pauv, ruaj khov, thiab cov khoom siv hluav taws xob piv rau lawv cov khoom tsis muaj fluorinated.

Kev sib txuas ntawm fluoro-hloov naphthalenes, xws li 6-Fluoronaphthalen-2-OL, suav nrog ntau yam tswv yim, suav nrog cov tshuaj fluorination ncaj qha, kev sib txuas sib txuas, thiab kev siv cov fluoro-muaj cov tsev thaiv. Ib txoj hauv kev tseem ceeb suav nrog Julia-Kocienski olefination ua raws li oxidative photocyclization los qhia fluoro hloov mus rau hauv cov tub ntxhais naphthalene, muab txoj hauv kev rau regiospecifically fluorinated polycyclic aromatic hydrocarbons.

Specification of CAS: 13101-83-2|6-fluoronaphthalen-2-ol

Kev Tshawb Fawb Daim Ntawv Thov CAS: 13101-83-2|6-fluoronaphthalen-2-ol

Fluorescence Studies:

6-Fluoronaphthalen-2-OL derivatives, xws li 6-acryloyl-2-dimethylaminonaphthalene (Acrylodan), yog siv los ua thiol-xaiv, polarity-sensitive fluorescent probes, tshwj xeeb tshaj yog nyob rau hauv cov kev tshawb fawb protein ( Prendergast et al., 1983).

6-Fluoronaphthalen-2-OL-based compounds, xws li 2-Bromoacetyl-6-methoxynaphthalene, ua hauj lwm ua fluorescent labeling reagents rau high-performance kua chromatography (HPLC) tsom xam ntawm carboxylic acids ( Gatti et al., 1992).

Tshuaj Synthesis:

6-Fluoronaphthalen-2-OL derivatives yog siv los tsim cov organic molecules complex. Piv txwv li, ib qho kev sib xyaw ua ke ntawm 1-(8-Fluoronaphthalen-1-yl)piperazine tau tsim, kov yeej cov kev sib tw hauv cov txheej txheem dhau los (Zhu Zhijian li al., 2007).

Cov compound tseem koom nrog hauv kev hloov pauv-hlau-dawb synthesis ntawm fluorinated naphthols, ua qauv qhia tshiab rau kev hloov pauv ntawm yooj yim 2-allyl-3-(trifluoromethyl) phenols rau hloov pauv 5-fluoronaphthalen{ {5}}ols (Hamman et al., 2014).

Kev siv tshuaj lom neeg:

6-Fluoronaphthalen-2-OL-raws li molecules, xws li 6-chloroacetyl-2-dimethylaminonaphthalene, tau raug tsim los ua fluorogenic substrates thiab tshuab sojntsuam rau glutathione hloov pauv hauv biochemistry (Svensson li al. , 2002).

Ib puag ncig-sensitive fluorophores xws li 6-N, N-dimethylamino-2, 3-naphthalimide (6DMN), muab los ntawm 6-Fluoronaphthalen-2- OL, yog siv los ua lom probes, nthuav tawm cov khoom fluorescent muaj txiaj ntsig hauv kev saib xyuas cov protein-protein kev sib cuam tshuam (Vázquez li al., 2005).

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