Taw qhia ntawm CAS: 960510-36-5|5-bromo-3, 6-dichloropyrazin-2-amine
5-Bromo-3, 6-dichloropyrazin-2-amine (5-Br-3,6-DCP) yog ib tug tswv cuab ntawm pyrazin -2-amine tsev neeg ntawm cov tebchaw, ib pawg ntawm nitrogen-muaj heterocyclic compounds. 5-Br-3,6-DCP yog lub zog thiab ntau yam reagent siv nyob rau hauv ntau yam kev sim sim thiab kev tshawb fawb kev tshawb fawb. Nws yog xim tsis muaj xim, crystalline khoom nrog qhov hnyav molecular ntawm 213.03 g / mol. 5-Br-3,6-DCP yog ib tug muaj zog oxidizing neeg sawv cev thiab tau siv nyob rau hauv ntau yam khoom siv hluavtaws organic chemistry. Tsis tas li ntawd, 5-Br-3,6-DCP tau siv rau hauv kev tshawb fawb biochemical thiab lub cev los kawm txog cov txheej txheem ntawm kev ua ntawm ntau lub tebchaw.
Specification of CAS: 960510-36-5|5-bromo-3, 6-dichloropyrazin-2-amine
|
Yam khoom |
SPECIFICATION |
|
Molecular Formula |
C4H2BrCl2N3 |
|
Purity |
97% |
|
Qhov ntom |
{{0}}.957± 0.06 g/cm3 (Tshaj tawm) |
|
Molecular Luj |
242.89 |
|
Kev cia khoom |
nyob rau hauv inert gas (nitrogen los yog Argon) ntawm 2-8 degree |
Kev Tshawb Fawb Daim Ntawv Thov CAS: 960510-36-5|5-bromo-3, 6-dichloropyrazin-2-amine
Catalytic Amination
5-Bromo-3, 6-dichloropyrazin-2-amine yog siv rau hauv cov txheej txheem catalytic amination. Piv txwv li, amination ntawm polyhalopyridines, xws li 5-bromo-2- chloropyridine, yog catalyzed los ntawm ib tug palladium-Xantphos complex, uas ua rau cov yields siab thiab zoo heev chemoselectivity, raws li tau pom nyob rau hauv kev tshawb fawb los ntawm Ji, Li, thiab Bunnelle (2003) (Jianguo Ji, Tao Li, & W. Bunnelle, 2003).
Regioselective Nucleophilic Aromatic Hloov
Cov compound tseem ceeb heev hauv regioselective nucleophilic aromatic hloov (S(N) Ar) cov tshuaj tiv thaiv. Kev tshawb fawb los ntawm Scales et al. (2013) pom tias amines nyiam tawm tsam tsis sib haum xeeb 3,5-dichloropyrazines ntawm cov haujlwm tshwj xeeb raws li cov neeg hloov pauv cov khoom siv hluav taws xob rho tawm lossis pub dawb (S. Scales li al., 2013).
Synthesis thiab Crystal Structure Analysis
Kev tshawb fawb los ntawm Doulah et al. (2014) koom nrog cov tshuaj regioselective hloov chaw ntawm ammonia nrog 5-bromo-2, 4-dichloro-6-methyl- pyrimidine, ua rau kev sib txuas ntawm 5-bromo{ {7}}chloro-6-methylpyrimidin-4-amine, ib qho tshuaj sib txuas nrog rau 5-Bromo-3, 6-dichloropyrazin-2-amine. Txoj haujlwm no tau hais txog kev siv hluav taws xob ntawm X-ray crystallography hauv kev tshuaj xyuas cov qauv siv lead ua ntawm cov khoom sib txuas (A. Doulah li al., 2014).
Coordination Polymers Tsim
Hauv thaj chaw ntawm inorganic chemistry, 5-Bromo-3, 6-dichloropyrazin-2-amine plays lub luag haujlwm hauv kev tsim cov polymers sib koom ua ke. Mailman et al. (2020) tau qhia txog kev tsim cov polymers sib koom tes nrog tooj liab (I) bromide, koom nrog kev sib txuas ntawm halogen thiab hydrogen bonding (A. Mailman li al., 2020).
Chemo- thiab Regioselective Reactions
Lub compound tseem ceeb heev hauv chemo- thiab regioselective cov tshuaj tiv thaiv. Piv txwv li, Moraes et al. (2019) tau piav qhia txog cov tshuaj tiv thaiv ntawm 5-bromo enones nrog pyrazoles, yielding npaj txhij txog N, O-aminal derivatives, qhia nws cov khoom siv hauv cov organic synthesis (Paulo A. Moraes li al., 2019).
Electrochemical Studies
Hauv kev tshawb fawb electrochemical, kev tshawb fawb sib piv ntawm cov txheej txheem redox ntawm Quinoxaline thiab Brimonidine, suav nrog 5-Bromo-3, 6-dichloropyrazin-2-amine, tau ua tiav kom nkag siab txog lawv cov kinetic thiab thermodynamic tsis, raws li kev tshawb fawb los ntawm Rupar li al. (2018) (J. Rupar et al., 2018).


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