Taw qhia ntawm CAS: 2445-83-2|7-METHYLCOUMARIN
Kev sib xyaw ntawm 7-Methylcoumarin feem ntau ua tiav los ntawm Pechmann condensation reaction34. Txoj kev no suav nrog cov condensation ntawm resorcinol nrog ethyl acetoacetate nyob rau hauv kev cuam tshuam ntawm ntau yam Lewis acids3. Cov tshuaj tiv thaiv tshwm sim los ntawm peb-kauj ruam mechanism: transesterification, intramolecular hydroxylalkylation, thiab lub cev qhuav dej 4.
Pechmann cov tshuaj tiv thaiv ntawm 7-Methylcoumarin los ntawm resorcinol thiab ethyl acetoacetate nrog sulfuric acid raws li ib tug catalyst tau raug npaj los ua ib tug peb-kauj ruam mechanism: transesterification, intramolecular hydroxylalkylation, thiab lub cev qhuav dej 4.
7-Methylcoumarin yog cov xim tsis muaj kob crystalline. Nws yog ruaj khov yog tias khaws cia kom zoo thiab yuav tsum tau ceev kom deb ntawm cov oxidizing muaj zog 9. Nws muaj qhov hnyav molecular ntawm 160.17 thiab molecular mis ntawm C10H8O29.
Specification of CAS: 2445-83-2|7-METHYLCOUMARIN
|
Yam khoom |
SPECIFICATION |
|
Melt point |
128-130 degree (lit.) |
|
Boiling point |
171-172 degree / 11 mmHg (lit.) |
|
Qhov ntom |
1.0924 (zeeg) |
|
Refractive Index |
1.5300 (kwv yees) |
Kev Tshawb Fawb Daim Ntawv Thov CAS: 2445-83-2|7-METHYLCOUMARIN
Antioxidant thiab Dawb Radical Scavenging Properties
7-Hydroxy-4-methylcoumarin thiab nws cov derivatives tau raug tsim thiab tshuaj xyuas rau lawv cov haujlwm antioxidant tiv thaiv hydrogen peroxide. Cov tebchaw no tau nthuav tawm cov kev ua ub no zoo heev, piv rau cov tshuaj antioxidants zoo li vitamin C, muab lub hauv paus rau lawv siv hauv oxidative kev nyuab siab ntsig txog (Al-Amiery li al., 2015).
Antifouling Agent
7-Hydroxy-4-methylcoumarin tau raug tshuaj xyuas rau nws cov khoom tiv thaiv fouling. Synthesized raws li ntsuab chemistry cov txheej txheem, qhov compound no zoo inhibited kev sib haum xeeb thiab byssogenesis ntawm mussels, qhia muaj zog antifouling los ntawm cov tsiaj nyob rau hauv marine ib puag ncig. Qhov no ua rau nws yog tus neeg sib tw tsim nyog rau cov txheej txheem tiv thaiv marine (Pérez li al., 2016).
Hepatoprotective nyhuv
7-Hydroxycoumarin tau pom muaj kev tiv thaiv tiv thaiv methyl glyoxal-induced toxicity thiab oxidative stress nyob rau hauv tib neeg HepG2 hlwb. Qhov kev tiv thaiv no cuam tshuam nrog kev cuam tshuam ntawm cov khoom siv hluav taws xob nuclear erythroid 2-txog yam 2 (NRF2) thiab nws cov enzymes downstream detoxifying, qhia txog nws lub peev xwm rau kev kho mob hauv cov kab mob uas cuam tshuam nrog methyl glyoxal (Li li al., 2017) .
Cim npe nrov: cas:2445-83-2|7-methylcoumarin, Tuam Tshoj cas:2445-83-2|7-methylcoumarin manufacturers, hoobkas
