CAS: 1261973-55-0|2-Cyano-5-(4-cyanophenyl)phenol

Taw qhia ntawm CAS: 1261973-55-0|2-Cyano-5-(4-cyanophenyl)phenol

3-Hydroxy-[1,1'-biphenyl]-4,4'-dicarbonitrile, tseem hu ua 3-hydroxy-4,4'-biphenyldicarbonitrile ({{12}) }HBCN) yog ntau yam thiab dav kawm cov organic compound. Nws yog cov xim tsis muaj xim nrog qhov hnyav molecular ntawm 218.22 g / mol thiab melting point ntawm 197-198 degree . 3-HBCN tau siv nyob rau hauv ntau yam kev tshawb fawb kev tshawb fawb, xws li nyob rau hauv kev sib txuas ntawm ntau yam ntawm cov organic tebchaw, nyob rau hauv kev tsim kho ntawm analytical cov tswv yim thiab nyob rau hauv kev tshawb fawb ntawm nws biochemical thiab physiological teebmeem.

Specification of CAS: 1261973-55-0|2-Cyano-5-(4-cyanophenyl)phenol

Kev Tshawb Fawb Daim Ntawv Thov CAS: 1261973-55-0|2-Cyano-5-(4-cyanophenyl)phenol

Cov ntawv thov tshawb fawb txog kev tshawb fawb

3-HBCN tau siv ntau yam kev tshawb fawb txog kev tshawb fawb, xws li hauv kev sib txuas ntawm ntau yam ntawm cov organic tebchaw, hauv kev txhim kho cov txheej txheem tshuaj ntsuam xyuas, thiab hauv kev tshawb nrhiav txog nws cov teebmeem biochemical thiab lub cev. 3-HBCN tau siv los ua cov khoom pib hauv kev sib txuas ntawm ntau cov organic tebchaw, xws li 2-methoxy-4-methyl-1,3-dioxolane{ {6}}carboxylic acid, 3-aminopropyl-4-methyl-1, 3-dioxolane-4-carboxylic acid, thiab 4-methyl{{13} }nitro{14}}, 3-dioxolane-4-carboxylic acid. Tsis tas li ntawd, 3-HBCN tau siv rau hauv kev txhim kho cov txheej txheem tshuaj ntsuam xyuas, xws li kev ua haujlwm siab ua kua chromatography (HPLC) txoj kev rau kev txiav txim siab ntawm 3-HBCN hauv cov tshuaj formulations. Ntxiv mus, 3-HBCN tau siv rau hauv kev tshawb xyuas ntawm nws cov biochemical thiab lub cev muaj zog, xws li nws cov teebmeem ntawm kev ua haujlwm ntawm cov enzymes, nws cov teebmeem ntawm kev loj hlob ntawm cov kab mob, thiab nws cov teebmeem ntawm cov tshuaj metabolism.

Mechanism ntawm Action

Cov txheej txheem ntawm kev ua ntawm 3-HBCN tsis to taub tag nrho. Txawm li cas los xij, nws ntseeg tau tias 3-HBCN tuaj yeem cuam tshuam nrog cov enzymes, xws li cytochrome P450 enzymes, thiab inhibit lawv cov haujlwm. Tsis tas li ntawd, 3-HBCN ntseeg tau tias tuaj yeem khi rau qhov chaw nquag ntawm cov enzymes thiab cuam tshuam nrog lawv cov kev ua haujlwm catalytic. Tsis tas li ntawd, 3-HBCN ntseeg tau tias tuaj yeem khi rau qhov chaw nquag ntawm cov enzymes thiab hloov lawv cov kev sib raug zoo, ua rau txo qis hauv lawv cov catalytic.

Biochemical thiab Physiological teebmeem

3-HBCN tau pom tias muaj ntau yam biochemical thiab physiological teebmeem. Piv txwv li, 3-HBCN tau pom tias inhibit qhov kev ua ntawm cytochrome P450 enzymes, uas koom nrog cov metabolism hauv cov tshuaj. Tsis tas li ntawd, 3-HBCN tau pom tias inhibit qhov kev loj hlob ntawm cov kab mob, xws li Escherichia coli, Salmonella typhimurium, thiab Staphylococcus aureus. Ntxiv mus, 3-HBCN tau pom tias muaj kev cuam tshuam rau cov metabolism hauv cov tshuaj, xws li tshuaj tua kab mob fluconazole.

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