Taw qhia ntawm CAS: 112006-75-4|2-Aminosulfonyl-N, N-dimethylnicotinamide
Synthesis Analysis
Cov synthesis ntawm "2-Aminosulfonyl-N, N-dimethylnicotinamide" tau piav qhia los ntawm ntau txoj hauv kev, qhia txog nws txoj kev nkag mus rau kev tshawb fawb thiab kev siv tshuab. Peng Xue-wei (2011) piav qhia txog txoj kev sib txuas pib los ntawm 2-chloronicotinic acid, koom nrog sulfhydrylation los ntawm thiourea kom ua tiav tag nrho cov txiaj ntsig ntawm 58.1% (Peng Xue-wei, 2011). Sun Jian (2006) ua kom zoo dua cov txheej txheem synthesis kom ua tiav cov txiaj ntsig siab dua ntawm 86%, kos qhov kev txhim kho tseem ceeb tshaj li txoj kev dhau los (Sun Jian, 2006).
Molecular Structure Analysis
Cov qauv molecular ntawm "2-Aminosulfonyl-N, N-dimethylnicotinamide" tau kawm ntau heev. Kev tshawb fawb los ntawm Stéphane Turcotte et al. (2012) ntawm N-Aminosulfamides, ze ze rau peb qhov kev txaus siab, tshawb nrhiav qhov hloov pauv ntawm C ( ) H thiab carbonyl ntawm cov amino acid residue nrog nitrogen atom thiab sulfonyl pawg, feem. Qhov kev tshawb fawb no muab kev nkag siab txog cov qauv molecular thiab muaj peev xwm rov ua haujlwm ntawm cov tebchaw no (Stéphane Turcotte, Samir Bouayad-Gervais, W. Lubell, 2012).
Specification of CAS: 112006-75-4|2-Aminosulfonyl-N, N-dimethylnicotinamide
|
Yam khoom |
SPECIFICATION |
|
Melt point |
198-209 degree (decomp) |
|
Boiling point |
488.9 ± 55. 0 degree (Predicted) |
|
Daim ntawv |
Khoom |
|
Xim |
Dawb rau Off-White |
|
Qhov ntom |
1.373 ± 0.06 g / cm3 (Tshaj tawm) |
|
Kev cia khoom |
nyob rau hauv inert gas (nitrogen los yog Argon) ntawm 2-8 degree |
Kev Tshawb Fawb Daim Ntawv Thov CAS: 112006-75-4|2-Aminosulfonyl-N, N-dimethylnicotinamide
Herbicide Intermediate: Nws yog ib qho tseem ceeb nruab nrab ntawm cov synthesis ntawm herbicide nicosulfuron. Kev ua kom zoo ntawm nws txoj kev siv hluavtaws tau ua kom pom tseeb kom muaj txiaj ntsig thiab purity. Cov txiaj ntsig thawj zaug tau nyob ib puag ncig 58.1% tab sis tom qab ntawd txhim kho mus rau 86% (Peng Xue-wei, 2011; Sun Jian, 2006; Li Yan-long, 2010).
Biomedical Applications: Pab pawg aminosulfonyl ua lub luag haujlwm tseem ceeb hauv kev xaiv ntawm qee qhov sib txuas ntawm enzyme inhibition, uas muaj txiaj ntsig zoo hauv kev tsim cov tshuaj tsom rau cov proteins lossis receptors (GL Grunewald li al., 1997).
Antibacterial thiab Antifungal Agents: Novel heterocyclic compounds incorporating the sulfamoyl moiety from 2-aminosulfonyl-N, N-dimethylnicotinamide qhia kev cog lus los tiv thaiv kab mob thiab cov kab mob fungal, qhia nws siv los tsim cov tshuaj tua kab mob (E. Darwish li al., 2014).
Environmental Cleanup: Cov khoom sib xyaw ua ke, tshwj xeeb tshaj yog nyob rau hauv cov ntsiab lus ntawm nicosulfuron, muaj kev txaus siab rau kev tu ib puag ncig thiab kev tshawb fawb biodegradation, qhia txog nws qhov tseem ceeb hauv kev txo cov pa phem thiab pab kho av (Weisong Zhao li al., 2015).
Chemical Synthesis & Polymer Research: Nws muaj cov ntawv thov hauv kev tsim cov tswv yim tshiab rau kev sib txuas ntawm hyperbranched polymers thiab ntau lwm cov tshuaj sib xyaw ua ke, uas qhia txog nws qhov kev ua tau zoo hauv cov khoom siv tshuaj lom neeg thiab cov khoom siv science (D. Yan & Chao Gao, 2000).


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