Taw qhiathiab kev siv ntawm CAS No. 76697-50-2|2-(Isopropylsulphonyl) aniline
2-(Isopropylsulphonyl)aniline (2-ISA) yog ib qho muaj zog thiab xaiv inhibitor ntawm mitotic checkpoint kinase Mad2, uas cuam tshuam rau kev mob qog noj ntshav. 2-ISA tau pom tias yuav txwv tsis pub lub mitotic spindle sib dhos checkpoint los ntawm kev khi rau Mad2 thiab inhibiting nws lub peev xwm los phosphorylate Mad1 thiab Cdc20. Cov kev sim hauv vitro tau pom tias 2-ISA thaiv cov kab mob ntawm tes hauv ht-29 hlwb, kab mob qog noj ntshav ntawm txoj hnyuv, los ntawm kev tiv thaiv lawv nkag mus rau hauv mitosis. 2-ISA tau pom tias yog ib qho zoo inhibitor ntawm cov qog loj hlob hauv vivo. Tus neeg sawv cev no tseem inhibits sorafenib, ib yam tshuaj uas tsom mus rau Raf / MEK / ERK txoj kev taw qhia thiab siv rau kev kho mob qog noj ntshav. Cov analogs ntawm 2-ISA tau raug tsim los ua cov tshuaj tiv thaiv kab mob.
Synonyms:
1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE;
1-Amino-2-(isopropylsulfonyl) benzene;
2-(Isopropylsulphonyl) aniline;
2-(Isopropylsulphonyl)aniline98%;
2-(isopropylsulfonyl) aniline;
2-(isopropylsulfonyl) benzenaMine;
2-(Propane-2-sulfonyl)-phenylaMine;
2-(Isopropylsulphonyl)aniline1-Amino-2-(isopropylsulfonyl)benzene
Specification ntawm CAS No. 76697-50-2|2-(Isopropylsulphonyl) aniline
|
Yam khoom |
SPECIFICATION |
|
CAS |
76697-50-2 |
|
MF |
C9H13NO2S |
|
MW |
199.27 |
|
Boiling point |
381.1 ± 34. 0 degree (Predicted) |
|
Qhov ntom |
1.194 ± 0.06 g / cm3 (Tshaj tawm) |
|
Melting point |
83.0 mus rau 87.0 degree |
|
acidity coefficient (pKa) |
{{0}}.79± 0.10(Thov) |
Pob thiab kev thauj mus losntawm Kev Taw Qhia thiab kev siv ntawmCAS No. 76697-50-2|2-(Isopropylsulphonyl) aniline
Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
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