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Taw qhiathiab daim ntawv thovntawm CAS No. 272-23-1|Thieno[2,3-b]pyridine
Thieno[2,3-b]pyridine yog ib qho quinoline derivative uas tau pom tias yog ib qho tshuaj tiv thaiv kab mob. Nws inhibits kev loj hlob ntawm tib neeg lub siab mob qog noj ntshav thiab tib neeg cov qog nqaij hlav cancer mis. Thieno[2,3-b]pyridine khi rau Pim-1 protein, uas tswj cov cell proliferation. Qhov kev cuam tshuam no thaiv kev ua kom lub zog ntawm cyclin D1 thiab inhibits kev tsim cov proteins qis xws li c-Myc, p27kip1, thiab cyclin E. Thieno[2,{10}}b]pyridine kuj inhibits cov haujlwm ntawm DNA topoisomerase I los ntawm kev khi rau nws qhov chaw nquag. Qhov inhibition ua rau tsub zuj zuj ntawm DNA tawg hauv cov qog hlwb uas tsis kho los ntawm cov enzyme no.
Synonyms:
Thieno[2,3-b]pyridine (8CI,9CI);
Specification ntawm CAS No. 272-23-1|Thieno[2,3-b]pyridine
|
Yam khoom |
SPECIFICATION |
|
CAS |
272-23-1 |
|
MF |
C7H5 NAS |
|
MW |
135.19 |
|
Qhov ntom |
1.272 ± 0.06 g / cm3 (Tshaj tawm) |
|
Boiling Point |
236.5 ± 13. 0 degree (Predicted) |
|
acidity coefficient (pKa) |
4.54 ± 0.30 (Tshaj tawm) |
|
Refractive Index |
1.689 |
|
Flash Point |
100.2ºC |
Package ua thiab kev thauj mus losntawm Kev Taw Qhia thiab kev siv ntawmCAS No. 272-23-1|Thieno[2,3-b]pyridine
Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
Cov ntawv txheebntawmCAS No. 272-23-1|Thieno[2,3-b]pyridine
Ib qho kev sib txuas, hauv silico, hauv vitro thiab hauv vivo kawm ntawm thieno [2, 3-b] pyridine anticancer analogues
HJ Arabshahi, M Van Rensburg, LI Pilkington… - …, 2015 - pubs.rsc.org
... moiety ntawm thieno[2,3-b]pyridines tau huv si ... SAR ntawm thieno[2,3-b]pyridines
los ntawm kev hloov pauv ntawm ... ntawm kev ua ntawm thieno[2,3-b] pyridines coj los ntawm molecular ...
Cim npe nrov: cas no.272-23-1|thieno[2,3-b]pyridine, China cas no.272-23-1|thieno[2,3-b]pyridine manufacturers, hoobkas
