CAS 1609392-27-9|BMS -986165

Taw qhiathiab daim ntawv thovntawm CAS 1609392-27-9|BMS -986165

BMS-986165 yog P-glycoprotein (P-gp) inhibitor uas tau pom tias txo qis kev nqus ntawm ciclosporin, tacrolimus, thiab everolimus hauv vitro. BMS-986165 muaj qhov Performance index ntawm 100% thiab inhibits inflammatory teb los ntawm inhibiting zus tau tej cov cytokines.

Nws tau pom tias muaj txiaj ntsig zoo rau kev kho cov kab mob hauv plab, xws li ulcerative colitis thiab Crohn's disease. Cov tshuaj kuj tseem siv tau los kho cov kab mob autoimmune, xws li psoriasis lossis mob caj dab rheumatoid. BMS -986165 yog siv los ntawm qhov ncauj thiab nqus tau sai. Nws yog metabolized los ntawm CYP3A4 thiab tawm hauv cov zis raws li metabolites.

Synonyms:

6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,{{8} }}triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide;

Specification ntawm CAS 1609392-27-9|BMS -986165

Package ua thiab kev thauj mus losntawm Kev Taw Qhia thiab kev siv ntawmCAS 1609392-27-9|BMS -986165

Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg

Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv

Cov ntawv txheebntawmCAS 1609392-27-9|BMS -986165

Kev xaiv ntau yam inhibition ntawm tyrosine kinase 2 (TYK2) rau kev kho mob ntawm cov kab mob autoimmune: nrhiav pom ntawm allosteric inhibitor BMS-986165

ST Wrobleski, R Moslin, S Lin, Y Zhang… - Journal of medicinal …, 2019 - ACS Publications

… Ntawm no peb qhia txog qhov kev ua kom zoo tshaj plaws rau theem kawg suav nrog kev tsim qauv tsim qauv thiab

Cov tswv yim hloov dej uas coj mus rau kev tshawb pom ntawm BMS-986165 (11) raws li kev sib raug zoo siab…

Cim npe nrov: cas 1609392-27-9|bms-986165, China cas 1609392-27-9|bms-986165 manufacturers, hoobkas