Taw qhiathiab daim ntawv thovntawm CAS 1802175-06-9 | CPI -360
CPI -360 yog ib yam tshuaj uas inhibits kev ua ntawm histone methyltransferases. Nws yog siv los kho mob qog noj ntshav, nrog rau lwm yam kab mob tshwm sim los ntawm kev hloov pauv ntawm cov noob caj noob ces. CPI -360 tau pom tias inhibit catalytic subunit ntawm methyltransferase. Ntxiv nrog rau kev tiv thaiv methylation ntawm histones, nws kuj inhibits transcriptional regulation thiab nucleosome los ua ke. Qhov zoo ntawm cov tshuaj no yog tias nws tsis cuam tshuam rau cov txheej txheem cellular methylation.
Synonyms:
1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-}oxo-3-pyridinyl)methyl]{ {10}}methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-;
N-[(1,2-Dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1- [(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide;
Specification ntawmCAS 1802175-06-9|CPI -360
|
Yam khoom |
SPECIFICATION |
|
CAS |
1802175-06-9 |
|
MF |
C25H31N3O4 |
|
MW |
437.53 |
|
Qhov ntom |
1.26 ± 0.1 g / cm3 (Tshaj tawm) |
|
Boiling point |
712.2 ± 6 0.0 degree (Predicted) |
|
acidity coefficient (pKa) |
11. {2}}1 ± 0.10 |
|
Solubility |
DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg / ml; Ethanol: PBS (pH7.2) (1:7): 0.12 mg/mL |
Package ua thiab kev thauj mus losKev taw qhia thiab kev siv CAS1802175-06-9|CPI -360
Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
Cov ntawv txheebCAS 1802175-06-9|CPI -360
[HTML] Lwm txoj hauv kev rau ChiP-Seq normalization ua kom pom kev hloov pauv ntawm genome-wide hauv histone H3 lysine 27 trimethylation thaum EZH2 inhibition
B Egan, CC Yuan, ML Craske, P Labhart, GD Guler… - PloS one, 2016 - journals.plos.org
… Spike-in normalization tsis cuam tshuam rau H3K9me3 teeb liab hauv hlwb kho nrog
CPI -360 rau 4 hnub thiab 8 hnub. (E) Scatter cov phiaj xwm sawv cev rau kev sib raug zoo ntawm tag nrho H3K27me3 thiab…
Cim npe nrov: cas:1802175-06-9|cpi-360, China cas:1802175-06-9|cpi -360 manufacturers, hoobkas
