Taw qhiathiab daim ntawv thovntawm CAS 1353016-71-3|DBCO-NHS Ester
DBCO-NHS ester yog cleavable ADC txuas rau kev sib txuas ntawm cov tshuaj tiv thaiv kab mob sib txuas (ADCs).
Dbco-nhs ester yog ib qho hluavtaws substrate uas yog siv rau kev npaj cov proteins los siv rau hauv kev kuaj mob thiab tshuaj xyuas chemistry. Cov khoom no tuaj yeem siv los txiav txim siab txog kev noj tshuaj thiab lwm yam tshuaj los ntawm cov ntshav capillaries, nrog rau kev ua haujlwm ntawm cov enzymes hauv cov qog nqaij hlav cancer. Dbco- nhs ester yog synthesized los ntawm 2, 4-dinitrobenzene sulfonic acid (db) thiab bovine serum albumin (BSA).
Nws tau pom tias khi rau tib neeg cov ntshav albumin hauv ib puag ncig aqueous. Cov khoom no kuj tseem tuaj yeem raug immobilized mus rau kev txhawb nqa khoom lossis siv hauv vivo ua qauv protein. Tsis tas li ntawd, dbco-nhs ester tej zaum yuav raug siv los kawm txog kev tiv thaiv kab mob ntawm cov hlwb thaum lawv raug coj los nrog cov khoom sib xyaw no.
Synonyms:
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester;
2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;
Dibenzylcyclooctyne-NHS ester;
DBCO-succinyl N-hydroxysuccinimidyl ester;
2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4- oxobutanoate;
Specification ntawmCAS 1353016-71-3|DBCO-NHS Ester
|
Yam khoom |
SPECIFICATION |
|
CAS |
1353016-71-3 |
|
MF |
C23H18N2O5 |
|
MW |
402.4 |
|
Qhov ntom |
1.43 ± 0.1 g / cm3 (Tshaj tawm) |
|
Boiling point |
67 0.2 ± 65.0 degree (Predicted) |
|
solubility |
Soluble hauv DMSO, DCM, DMF |
|
acidity coefficient (pKa) |
{{0}}.23 ± 0.20(Predicted) |
|
Kev ruaj ntseg |
Moisture Sensitive |
Package ua thiab kev thauj mus losKev Taw Qhia thiab daim ntawv thov CAS 1353016-71-3|DBCO-NHS Ester
Pob: 0.1g, 1g, 5g, 25g, 100g, 500g, 1kg
Kev thauj mus los: los ntawm courier / los ntawm huab cua / los ntawm hiav txwv
Cov ntawv txheebCAS 1353016-71-3|DBCO-NHS Ester
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Cim npe nrov: cas:1353016-71-3|dbco-nhs ester, Tuam Tshoj cas:1353016-71-3|dbco-nhs ester manufacturers, hoobkas
